52 elderly knee osteoarthritis patients who underwent a unilateral primary total knee replacement were randomized to receive 4 months of exergaming rehabilitation (videogame-based rehabilitation; n=25) or standard home-based exercise (n=27). The primary outcomes of interest were knee-related function and pain, and mobility. Secondary outcomes of interest included knee pain on a Visual Analog Scale (VAS), walking speed, lower extremity performance, muscle strength, knee range of motion, and satisfaction, assessed up to 4 months follow-up. The study revealed comparable results between the two groups for most outcomes; however, patients who received the exergaming program reported significantly better mobility improvement and a higher level of satisfaction compared to the standard group.