Accelerated surgery versus standard care in hip fracture (HIP ATTACK): an international, randomised, controlled trial

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研究概要

2970 patients with hip fractures were randomized to receive either accelerated surgery (n=1487) or standard of care (n=1483). The co-primary outcomes of interest included mortality and a composite outcome of major complications (i.e., mortality, non-fatal myocardial infarction, stroke, venous thromboembolism, sepsis, pneumonia, life-threatening bleeding, and major bleeding) after 90 days. Secondary outcomes of interest included incidence of pressure ulcers, pneumonia, infection, sepsis, residential status, delirium, and length of stay. Rapid treatment leads to notable decreases in delirium, non-sepsis infections, and hospitalization duration without a rise in medical complications or death rates. Furthermore, patients with high baseline troponin levels experienced a marked reduction in mortality when receiving accelerated care.