COA 2020: Factors Predicting Multiple Surgeries for Paediatric Osteomyelitis - The CORTICES group .
OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2025;13(6):32A total of nine hundred and ninety-six paediatric patients who had osteomyelitis were included in the study. Sixteen percent of included patients required more than 1 surgery; factors associated with an increase in probability of needed more than 1 surgery for treatment of OM included a higher white blood cell count, peak C-reative protein, peak erythrocyte sedimentation rate and lower platelet count.
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Why was this study needed now?
It is important to understand musculoskeletal infections in children, including paediatric osteomyelitis. Surgical treatment is often used, and assessing factors that can increase the likelihood of requiring more than 1 surgery is crucial.
What was the principal research question?
What factors can predict whether children with paediatric osteomyelitis (OM) require multiple surgery for treatment?
- Of a total of 996 patients with OM, 16% required more than 1 surgery.
- Results revealed that significant differences were found for factors including white blood cell count, lowest platelet count, peak C-Reactive protein, and peak erythrocyte sedimentation rate.
- Children with all of the above mentioned risk factors had a 62% increase in probability of needing more than 1 surgery, where as a child with no risk factors had a 4% probability.
What should I remember most?
Children with paediatric OM are at an increased probability of requiring multiple surgeries if they have higher white blood cell count, C-Reactive protein, and peak erythrocyte sedimentation rate along with lower platelet values.
How will this affect the care of my patients?
It can inform clinicians and physicians in helping make clinical decisions during the treatment of OM in paediatric patients.
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