Allograft vs. Bioactive Glass for Pediatric Benign Bone Lesions: A Randomized Trial .
Allograft Versus Bioactive Glass (BG-S53P4) in Pediatric Benign Bone Lesions: A Randomized Clinical Trial.
J Bone Joint Surg Am. 2023 May 3;105(9):659-666.51 children with benign bone cysts were randomized to receive intralesional curettage and filling with an allograft (n=26) or with bioactive glass (n=25) the primary outcome of interest was the volume of recurrent cysts at 24 months follow-up. Secondary outcomes of interest included the recurrence rate, risk of re-operation, Musculoskeletal Tumour Society (MSTS) Score, and complications. The results showed no difference in all outcomes between the two filling materials. Reoperation was more difficult for patients who received bioactive glass due to the hard mixture of glass and newly formed bone. With no differences in lesion recurrence volume or rate, bioactive glass didn't provide any advantage over allografting.
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