Antegrade intramedullary nailing the favoured procedure for fifth metacarpal neck fracture .
OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2014;2(10):39 Eur J Orthop Surg Traumatol. 2014 Apr;24(3):273-8. doi: 10.1007/s00590-013-1344-5. Epub 2013 Oct 27.4 studies (3 quasi-randomized trials and 1 randomized controlled trial) comparing antegrade intramedullary nailing (AIMN) with other surgical interventions for fifth metacarpal neck fractures were included in this review to compare treatment efficacy. Pooled data demonstrated trends favouring AIMN for pain scores, the incidence of complications and mean residual angulation at the site of fracture. Additionally, AIMN yielded significantly greater grip strength at 12 months and improved range of motion of the metacarpophalangeal joint. When compared to transverse pinning (TP) with K-wires, AIMN yielded significantly better total active motion and greater patient satisfaction.
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Were the criteria used for deciding which studies to include in the overview reported?
Was the bias in the selection of studies avoided?
Were the criteria used for assessing the validity of the included studies reported?
Was the validity of all of the studies referred to in the text assessed with use of appropriate criteria (either in selecting the studies for inclusion or in analyzing the studies that were cited)?
Were the methods used to combine the findings of the relevant studies (to reach a conclusion) reported?
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Ja = 1
Ungewiss = 0.5
Nicht relevant = 0
Nein = 0
Die Bewertung der Berichtskriterien bewertet die Transparenz, mit der die Autoren die methodischen und studienspezifischen Merkmale der Studie in der Veröffentlichung angeben. Die Bewertung ist in fünf Kategorien unterteilt, die im Folgenden vorgestellt werden.
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Introduction
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Accessing Data
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Analysing Data
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Results
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Discussion
Detsky AS, Naylor CD, O'Rourke K, McGeer AJ, L'Abbé KA. J Clin Epidemiol. 1992;45:255-65
Der Fragilitätsindex ist ein Instrument, das bei der Interpretation signifikanter Ergebnisse hilft und ein Maß für die Stärke eines Ergebnisses liefert. Der Fragilitätsindex gibt die Anzahl der aufeinanderfolgenden Ereignisse an, die zu einem dichotomen Ergebnis hinzugefügt werden müssen, damit das Ergebnis nicht mehr signifikant ist. Eine kleine Zahl steht für ein schwächeres Ergebnis und eine große Zahl für ein stärkeres Ergebnis.
Warum wurde diese Studie jetzt benötigt?
Fractures of the neck of the fifth metacarpal, also known as boxer's fractures, are common and may require surgical intervention. The clinical recommendations regarding the optimal conditions for surgical intervention, however, are inconsistent in the literature. Operative procedures to treat this type of fracture include antegrade intramedullary nailing (AIMN), retrograde pinning (RP) or transverse pinning (TP) using intramedullary K-wires, external fixation, and standard plates. Although AIMN is less invasive and is commonly used in clinical practice, evidence is conflicted regarding the superiority of its efficacy over other surgical treatment approaches.
Was war die wichtigste Forschungsfrage?
When treating fifth metacarpal neck fractures, is antegrade intramedullary nailing (AIMN) more efficacious than other surgical interventions?
- 4 studies (3 quasi-randomized trials and one randomized controlled trial) were included in this meta-analysis. In total, 163 patients were included (mean age 29.1 years [range 18-65]).
- There was no significant difference between groups with respect to pooled pain scores from 3 studies (n=133; MD -0.18; 95% CI -0.528 to 0.154; p=0.2; I-squared 0%).
- Quick DASH scores were reported in one study, demonstrating no significant difference between AIMN and plates.
- Although there was no significant difference between AIMN and plates in grip strength at 3-6 months (2 studies; MD -0.28; 95% CI -0.773 to 0.204; p=0.2), AIMN yielded significantly greater grip strength at 12 months compared to either plates or transverse pinning (3 studies; MD 0.84; 95% CI 0.468 to 1.206; p<0.0001; I-squared 54.5%).
- When compared to transverse pinning (TP) with K-wires, AIMN resulted in significantly greater total active motion at 12 months (2 studies; pooled effect size 0.5; 95% CI 0.087 to 0.904; p=0.01; Q: p=0.316). In the only study reporting patient satisfaction following TP and AIMN, 15/16 patients (94%) in the AIMN group were either "satisfied" or "very satisfied", which was likewise displayed by 13/17 patients (76.5%) in the TP group.
- With respect to range of motion of the metacarpophalangeal joint, one study, at a follow-up of <6 months, reported a significant difference in favour of AIMN (p=0.001). At 12 months, pooled data from three studies also found a significant difference in favour of AIMN (pooled effect size 1.45; 95% CI 0.787 to 2.106; p<0.0001; I-squared 55.9%).
- The incidence of complications was lower with AIMN compared to all other surgical interventions, with this difference being borderline-significant (OR 0.4; 95% CI 0.155 to 1.028; p=0.05; I-squared 0%).
- Pooled data on mean residual angulation at the site of fracture from 3 studies favoured AIMN, with the difference being borderline significant (pooled effect size -0.4; 95% CI -0.779 to 0.000042; p=0.05; I-squared 0%).
Was sollte ich mir besonders merken?
Trends favouring antegrade intramedullary nailing (AIMN) were found for pain scores, the incidence of complications and mean residual angulation at the site of fracture. Additionally, AIMN yielded significantly greater grip strength at 12 months and range of motion of the metacarpophalangeal joint. When compared to transverse pinning (TP) with K-wires, AIMN yielded significantly better total active motion and greater patient satisfaction.
Wie wird sich dies auf die Behandlung meiner Patienten auswirken?
Results from this study suggest antegrade intramedullary nailing (AIMN) may provide additional clinical benefits when compared to other forms of surgical intervention for patients with fifth metacarpal neck fractures. Future studies are needed to conduct head-to-head comparisons between various surgical interventions and AIMN, as opposed to grouping surgical approaches as one comparison group.
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