Multicentre randomised controlled clinical trial of electroacupuncture with usual care for patients with non-acute pain after back surgery

この研究はインパクトが大きい可能性があると判断されました。 OEのAIによるハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文の影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することができ、読者は将来の診療を形成する可能性が最も高い論文に焦点を当てることができます。

研究概要

One hundred and eight patients with non-acute low back pain after back surgery were randomized to receive 4 weeks of physical therapy and education with electroacupuncture treatment (n=54) or without acupuncture treatment (n=54). The primary outcome of interest was pain scores on a 100 point Visual Analog Scale (VAS). Secondary outcomes of interest included the Oswestry Disability Index (ODI), the Euro Quality of Life 5 Dimension (EQ-5D) quality of life questionnaire, and the incidence of adverse events. Outcomes were assessed at 3, 5, 8 and 12 weeks follow-up for VAS pain scores and ODI scores, as well as 5, 8 and 12 weeks for EQ-5D scores. Adverse events were assessed at each follow-up time-point. Results revealed statistically significantly lower VAS pain scores in the electroacupuncture group compared to the control group at 3 weeks (p=0.0063) and 5 weeks (p=0.0311) follow-up. Additionally, ODI scores were statistically significantly in favour of the electroacupuncture group at 3, 5 and 8 weeks follow-up (p<0.05 for all). No statistically significant differences were observed between the two groups in EQ-5D scores at all timepoints (p>0.05 for all). Moreover, 1 patient in the electroacupuncture group and 3 patients in the control group required additional treatment (p=0.6179). In the electroacupuncture group, 29 adverse events were reported, as well as 2 cases of hospitalization for traffic accidents. In the control group, 24 adverse events were reported, as well as 1 cases of hospitalization for appendicitis, 1 case of cystitis, and 3 cases of pain aggravation.