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ACL reconstruction: BPTB graft has better stability but more complications than hamstring
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SPORTS MEDICINE
ACL reconstruction: BPTB graft has better stability but more complications than hamstring .

OrthoEvidence Journal (OE Journal) - ACE Report

OE Journal. 2013;1(11):286 Arch Orthop Trauma Surg. 2012 Sep;132(9):1287-97. doi: 10.1007/s00402-012-1532-5. Epub 2012 Jun 3
Autores contribuintes

S Li Y Chen Z Lin W Cui J Zhao W Su

This meta-analysis and systematic review identified 9 randomized controlled trials comparing hamstring (HT) autografts and bone-patellar tendon-bone (BPTB) autografts in patients undergoing anterior cruciate ligament (ACL) reconstruction. The analysis indicated that the HT autograft group had a significantly lower proportion of patients with a negative Pivot test than the BPTB autograft group. However, fewer patients in the HT group experienced post-operative anterior knee pain and kneeling pain compared to the BPTB group.


Detalhes do financiamento da publicação +
Financiamento:
Not Reported
Conflicts:
None disclosed

Risco de viés

10/10

Critérios de notificação

17/20

Índice de Fragilidade

N/A

Were the search methods used to find evidence (original research) on the primary question or questions stated?

Was the search for evidence reasonably comprehensive?

Were the criteria used for deciding which studies to include in the overview reported?

Was the bias in the selection of studies avoided?

Were the criteria used for assessing the validity of the included studies reported?

Was the validity of all of the studies referred to in the text assessed with use of appropriate criteria (either in selecting the studies for inclusion or in analyzing the studies that were cited)?

Were the methods used to combine the findings of the relevant studies (to reach a conclusion) reported?

Were the findings of the relevant studies combined appropriately relative to the primary question that the overview addresses?

Were the conclusions made by the author or authors supported by the data and or analysis reported in the overview?

How would you rate the scientific quality of this evidence?

Sim = 1

Incerto = 0,5

Não relevante = 0

Não = 0

A Avaliação dos Critérios de Relato avalia a transparência com que os autores relatam as caraterísticas metodológicas e do ensaio na publicação. A avaliação está dividida em cinco categorias que são apresentadas de seguida.

4/4

Introduction

3/4

Accessing Data

3/4

Analysing Data

4/4

Results

3/4

Discussion

Detsky AS, Naylor CD, O'Rourke K, McGeer AJ, L'Abbé KA. J Clin Epidemiol. 1992;45:255-65

O Índice de Fragilidade é uma ferramenta que auxilia na interpretação de achados significativos, fornecendo uma medida de força para um resultado. O Índice de Fragilidade representa o número de eventos consecutivos que precisam de ser adicionados a um resultado dicotómico para que o resultado deixe de ser significativo. Um número pequeno representa um resultado mais fraco e um número grande representa um resultado mais forte.

Porque é que este estudo era necessário agora?

There is currently much debate regarding the optimal type of graft that for ACL reconstruction. While autografts have been considered superior to allografts, it is still uncertain as to which type of autograft is best. HT autografts have been associated with a lower risk of donor site morbidity than BPTB autografts, whereas BPTB grafts have been shown to be more stable than the HT alternative. This meta-analysis and systematic review, therefore, aimed to include only randomized controlled trials in comparing the effectiveness of HT and BPTB autografts in patients undergoing ACL reconstruction.

Qual era a principal questão de investigação?

Is there a difference between HT and BPTB autografts with regard to stability, function, and complications in patients undergoing ACL reconstruction?

Caraterísticas do estudo +
Data Source:
A search for articles published up until December 2011 was conducted using the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE and EMBASE.
Index Terms:
Index terms included ACL, reconstructive surgical procedures, transplants, autologous, patellar ligament, HS, hamstrings, semitendinosus and gracilis.
Study Selection:
Studies included were randomized controlled trials comparing HT and BPTB autografts in unilateral ACL reconstruction. Outcomes of interest included IKDC scores, Lachman test, Pivot test, anterior keen and kneeling pain, extension and flexion loss, graft failure, infection rate, and reoperations asociated with meniscal and patellofemoral crepitation. Studies were selected by two independent reviewers and disagreements were resolved by discussion or a third author.
Data Extraction:
Data was extracted by two independent reviewers. Disagreements were resolved through discussion or by a third reviewer.
Data Synthesis:
Review Manager was used to compile the data. Dichotomous outcomes were expressed as relative risk (RR) ratios with 95% confidence intervals (CI). A fixed-effects model was used when there was no significant heterogeneity, and a random-effects model was used when heterogeneity was calculated. Heterogeneity was calculated using a chi squared test, in which p<0.1 was considered significant.
Quais foram os resultados importantes?
  • According to 8 studies, the two autografts did not differ with respect to post-operative knee joint function (IKDC scores) (RR 1.05, 95 % CI 0.93-1.19, p=0.41)
  • The pooled data from 5 studies indicated that there was no significant difference between the two types of autografts for the proportion of patients with negative Lachman test results (RR 0.65, 95 % CI 0.18-2.34, p=0.51)
  • According to 6 studies, the BPTB autograft resulted in a higher proportion of patients with a negative Pivot test than the HT autograft (RR 0.87, 95 % CI 0.79-0.96, p=0.004)
  • The HT group demonstrated a lower incidence of post-operative anterior knee pain (4 studies) (RR 0.66, 95 % CI 0.45-0.96, p=0.03) and kneeling pain (6 studies) (RR 0.49, 95 % CI 0.27-0.91, p=0.02) than the BPTB group
  • From 5 studies, extension loss of 5 degrees or greater was seen in 26 out of 219 HT group patients and 29 out of 178 BPTB group patients (RR 0.63, 95% CI 0.39-1.01); from 3 studies, flexion loss of 5 degrees or more was seen in 62 of 141 HT patients and 37 of 105 BPTB patients (RR 1.03, 95 % CI 0.78-1.35)
  • There was no difference between the two groups for the incidence of graft failure (8 studies; RR 1.37, 95 % CI 0.67-2.81, p=0.38), infection rate (6 studies; RR 1.04, 95 % CI 0.46-2.35, p=0.93), and rate of reoperation related to the meniscus (RR 1.78, 95 % CI 0.75-4.22, p=0.19)
De que é que me devo lembrar mais?

The results suggested that bone-patellar tendon-bone (BPTB) autografts were superior to hamstring autografts with respect to the resulting knee joint stability after ACL reconstruction. However, the hamstring graft resulted in fewer complications (anterior knee pain, and pain when kneeling) than the BPTB graft.

Como é que isto afectará o tratamento dos meus doentes?

Using a BPTB autograft for ACL reconstruction results in greater rotational stability compared to using a hamstring autograft as assessed with the Pivot shift test at the expense of a higher likelihood of anterior knee pain and kneeling pain.Although patients who received the BPTB autograft tended to demonstrate better recovery of knee joint stability than those who received the hamstring graft, a greater incidence of anterior knee pain and kneeling pain was seen in the BPTB patients than the hamstring group patients.

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OrthoEvidence. ACL reconstruction: BPTB graft has better stability but more complications than hamstring. OE Journal. 2013;1(11):286. Available from: https://myorthoevidence.com/AceReport/Show/acl-reconstruction-bptb-graft-has-better-stability-but-more-complications-than-hamstring

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