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Surgical treatment of scaphoid waist fractures associated with high risk of complications
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GENERAL ORTHOPAEDICS
Surgical treatment of scaphoid waist fractures associated with high risk of complications .
Verified
This report has been verified by one or more authors of the original publication.
High Impact
Este estudo foi identificado como tendo um impacto potencialmente elevado. A métrica de Alto Impacto da OE, baseada em IA, estima a influência que um artigo poderá ter, integrando sinais da revista em que foi publicado e do conteúdo científico do próprio artigo. Desenvolvido com recurso ao mais avançado processamento de linguagem natural, o modelo High Impact da OE prevê com maior precisão o desempenho futuro de um estudo em termos de citações do que o fator de impacto da revista por si só. Isto permite o reconhecimento precoce de investigação clinicamente significativa e ajuda os leitores a concentrarem-se nos artigos com maior probabilidade de moldar a prática futura.

OrthoEvidence Journal (OE Journal) - ACE Report

OE Journal. 2013;1(17):4 J Hand Surg Am. 2011 Nov;36(11):1759-1768.e1. doi: 10.1016/j.jhsa.2011.08.033
Autores contribuintes

T Ibrahim A Qureshi AJ Sutton JJ Dias

6 studies (363 patients) examining outcomes of surgical and nonsurgical treatments of undisplaced or minimally displaced scaphoid waist fractures were evaluated through pairwise meta-analysis. An additional 3 trials were also identified for inclusion in a network meta-analysis. Following assessments of fracture union, complications, range of motion, grip strength, and osteoarthritis between patients who underwent either surgical or non-surgical treatment, there was a non-significant trend to increased union with surgical treatment. However this method of treatment was also associated with a higher risk of complications.


Detalhes do financiamento da publicação +
Financiamento:
Non-funded
Conflicts:
None disclosed

Risco de viés

10/10

Critérios de notificação

17/20

Índice de Fragilidade

N/A

Were the search methods used to find evidence (original research) on the primary question or questions stated?

Was the search for evidence reasonably comprehensive?

Were the criteria used for deciding which studies to include in the overview reported?

Was the bias in the selection of studies avoided?

Were the criteria used for assessing the validity of the included studies reported?

Was the validity of all of the studies referred to in the text assessed with use of appropriate criteria (either in selecting the studies for inclusion or in analyzing the studies that were cited)?

Were the methods used to combine the findings of the relevant studies (to reach a conclusion) reported?

Were the findings of the relevant studies combined appropriately relative to the primary question that the overview addresses?

Were the conclusions made by the author or authors supported by the data and or analysis reported in the overview?

How would you rate the scientific quality of this evidence?

Sim = 1

Incerto = 0,5

Não relevante = 0

Não = 0

A Avaliação dos Critérios de Relato avalia a transparência com que os autores relatam as caraterísticas metodológicas e do ensaio na publicação. A avaliação está dividida em cinco categorias que são apresentadas de seguida.

4/4

Introduction

3/4

Accessing Data

4/4

Analysing Data

3/4

Results

3/4

Discussion

Detsky AS, Naylor CD, O'Rourke K, McGeer AJ, L'Abbé KA. J Clin Epidemiol. 1992;45:255-65

O Índice de Fragilidade é uma ferramenta que auxilia na interpretação de achados significativos, fornecendo uma medida de força para um resultado. O Índice de Fragilidade representa o número de eventos consecutivos que precisam de ser adicionados a um resultado dicotómico para que o resultado deixe de ser significativo. Um número pequeno representa um resultado mais fraco e um número grande representa um resultado mais forte.

Porque é que este estudo era necessário agora?

When scaphoid waist fractures occur they should be immobilized in order to allow for anatomical union and to prevent midcarpal arthrosis and carpal malalignment. Treatment can occur either surgically or non-surgically using a cast, but it is still unknown which method is the most effective. Hence, this meta-analysis aimed to compare the odds ratio of fracture union, complications, and other clinical outcomes of surgical and nonsurgical treatment of scaphoid waist fractures.

Qual era a principal questão de investigação?

Was surgical treatment of scaphoid waist fractures more effective than nonsurgical treatments, in terms of the odds ratio of fracture union?

Caraterísticas do estudo +
Data Source:
Online databases that were searched were MEDLINE, EMBASE, Web of Science, Elsevier Scopus and Cochrane Registry of Clinical Trials
Index Terms:
The index terms searched were 'scaphoid fractures' combined with either 'surgery', 'cast immobilization', 'randomized controlled trial', 'random allocation', or 'randomization'
Study Selection:
Two authors independently examined each study. Studies were included in the pairwise meta-analysis if they were randomized controlled trials that compared surgical and nonsurgical treatment of scaphoid waist fractures and provided the rate of fracture union. In the network meta-analysis, all randomized controlled trials were included if they compared any type of scaphoid waist fracture treatments and provided the rate of fracture union.
Data Extraction:
Two investigators independently extracted data on study characteristics, interventions, outcome definition, sample size, number of fracture unions between surgical and nonsurgical treatments, and number of patients with complications. Any discrepancies were resolved through consensus.
Data Synthesis:
Pairwise meta-analysis: Studies were pooled and Forest plots were constructed using the DerSimonian-Laird random effects model. The I-squared statistic was used to quantify heterogeneity. A pairwise comparison of the pooled complication rate, range of motion, grip strength, and osteoarthritis were conducted and were reported as means and 95% confidence intervals (CI). Network meta-analysis: Statistical analysis of data was achieved using a Bayesian Markov chain Monte Carlo method with the software WinBUGS
Quais foram os resultados importantes?
  • In the Pairwise meta-analysis there were 6 studies included (7 publications) that compared non –operative and operative treatment of scaphoid waist fractures. The Network meta-analysis identified another 3 randomized controlled trials that compared 2 non-surgical treatments resulting in a total of 9 trials comparing 5 different treatment methods.
  • The Pairwise meta-analysis resulted in an overall pooled odds ratio of fracture union rate that was 2.36 (95% CI: 0.02, 8.9; p=0.210; I-squared: 0%). Although, the pooled odds ratio of fracture union rate was higher in the nonsurgical treatment patients (ratio: 3.10; 95% CI: 0.46, 21.05; p=0.250; I-squared: 0%) than in the surgical patients (ratio: 1.46; 95% CI: 0.11, 20.57; p=0.780; I-squared: 46.1%), this was not significant.
  • The Pairwise meta-analysis of complication rate had a pooled odds ratio of 6.96 (95% CI: 2.13, 27.73; p=0.001; I-squared: 0%), which indicated an elevated risk of complication for those undergoing surgical treatment.
  • Although the mean overall percentage difference in the range of motion (2.1%; 95% CI: -0.03, 0.08; p=0.430; I-squared: 61.4%) and grip strength (2.6%; 95% CI: -0.013, 0.066; p=0.190; I-squared: 0%) between the surgical and nonsurgical groups in the Pairwise Meta-analysis favoured surgery, these variations were not significant.
  • The pooled odds ratios for osteoarthritis of the scaphotrapeziotrapezoid joint (3.25; 95% CI: 0.073, 14.39; p=0.120; I-squared: 65.4%) between the surgical and nonsurgical groups favoured surgery, while the pooled odds ratios for osteoarthritis of the radiocarpal joint (0.75; 95% CI: 0.15, 3.82; p=0.730; I-squared: 67.2%) between the surgical and nonsurgical groups favoured nonsurgery, these differences were not statistically significant.
  • The Network meta-analysis assessed the odds ratio of fracture union for all possible pairwise comparisons. The results indicated that long and short thumb spica casts had the highest probability of being the best treatment (0.810). This was influenced by the lower number of non-unions in the solitary trial that compared these treatments.
De que é que me devo lembrar mais?

Although the pair-wise analysis indicated a higher fraction union rate for the surgical treatment, this difference was not significant. Furthermore, surgical treatment appeared to have a higher risk of developing complications.

Como é que isto afectará o tratamento dos meus doentes?

Patients should be aware that there is a risk of developing complications by undergoing surgical treatment for scaphoid waist fractures. Although fracture union rates appeared to be higher with surgery in this study, this difference was not significant and there is no clear evidence indicating a significant increased union rates with surgery. Unless new evidence is released, then patients should continue to be treated using nonsurgical treatments.

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OrthoEvidence. Surgical treatment of scaphoid waist fractures associated with high risk of complications. OE Journal. 2013;1(17):4. Available from: https://myorthoevidence.com/AceReport/Show/

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