OrthoEvidence - Search

General Orthopaedics
Protein Supplementation for Hip Fracture Recovery in Elderly Patients: A Randomized Controlled Trial.
J Orthop Trauma. 2026 01-Jun;():. 10.1097/BOT.0000000000003158

Osteoarthritis
Collagen protein supplementation does not modulate biomarkers of bone metabolism following total hip arthroplasty: a randomized, double-blind, placebo-controlled trial.
Clin Nutr ESPEN. 2026 01-Jun;():. 10.1016/j.clnesp.2026.103253

Physical Therapy & Rehab
Creatine- And HMB-Enriched Protein Supplementation For Hip Fracture Recovery In Elderly Patients: A Randomized Controlled Trial

Peri-Operative
Peri-Operative Oral Protein Supplementation Improves Muscle Power And Serum Biomarkers After Fragility Hip Fracture: A Systematic Review And Meta-Analysis

Osteoarthritis

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Effect of high plant protein/peptide nutrition supplementation on knee osteoarthritis in older adults with sarcopenia: A randomized, double-blind, placebo-controlled trial.
Clin Nutr. 2024 01-Aug;():. 10.1016/j.clnu.2024.07.037

Shoulder & Elbow
The level of ratio between matrix metalloproteinase-1 (MMP-1) and tissue inhibitor matrix metalloproteinase-1 (TIMP-1) after prolotherapy intervention and the functional outcome in patient with frozen shoulder: A randomized controlled trial.

This report has been verified by one or more authors of the original publication.

Medicine (Baltimore). 2023 01-Jul;():. 10.1097/MD.0000000000034356

Spine
Bone morphogenetic protein-2 against iliac crest bone graft for the posterolateral fusion of the lumbar spine: A meta-analysis
Int J Clin Pract. 2021 01-Apr;():. 10.1111/ijcp.13911

Osteoarthritis

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Clinical Outcomes of Knee Osteoarthritis Treated With an Autologous Protein Solution Injection: A 1-Year Pilot Double-Blinded Randomized Controlled Trial
Am J Sports Med. 2018 Jan;46(1):171-180.

Spine
Efficacy of Escherichia coli-derived recombinant human bone morphogenetic protein-2 in posterolateral lumbar fusion: an open, active-controlled, randomized, multicenter trial
Spine J. 2017 Dec;17(12):1866-1874

Spine
Union Rate and Complications in Spine Fusion with Recombinant Human Bone Morphogenetic Protein-7: Systematic Review and Meta-Analysis

This report has been verified by one or more authors of the original publication.

Global Spine J. 2016 Mar;6(2):124-32

Metabolic Disorders
Effects of protein-rich nutritional supplementation and bisphosphonates on body composition, handgrip strength and health-related quality of life after hip fracture: a 12-month randomized controlled study
BMC Geriatr. 2015 Nov 17;15(1):149

Trauma
Bone Morphogenetic Protein for the Healing of Tibial Fracture: A Meta-Analysis of Randomized Controlled Trials
PLoS One. 2015 Oct 28;10(10):e0141670.

Spine
Retrograde ejaculation following single-level anterior lumbar surgery with or without recombinant human bone morphogenetic protein-2 in 5 randomized controlled trials

This report has been verified by one or more authors of the original publication.

J Neurosurg Spine. 2013 Feb;18(2):112-21. doi: 10.3171/2012.10.SPINE11908. Epub 2012 Nov 30

Spine
A meta analysis of lumbar spinal fusion surgery using bone morphogenetic proteins and autologous iliac crest bone graft
PLoS One. 2014 Jun 2;9(6):e97049. doi: 10.1371/journal.pone.0097049. eCollection 2014.

Trauma
Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions

This report has been verified by one or more authors of the original publication.

J Bone Joint Surg Am. 2001;83-A Suppl 1(Pt 2):S151-8

Trauma

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients
J Bone Joint Surg Am. 2002 Dec;84-A(12):2123-34

Trauma

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Efficacy and Safety of Recombinant Human Bone Morphogenetic Protein-2/Calcium Phosphate Matrix for Closed Tibial Diaphyseal Fracture: A Double-Blind, Randomized, Controlled Phase-II/III Trial

This report has been verified by one or more authors of the original publication.

J Bone Joint Surg Am. 2013 Dec 4;95(23):2088-96. doi: 10.2106/JBJS.L.01545

Trauma
Bone morphogenetic protein: Is it only pixie dust? A meta-analysis

Spine

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Safety and Effectiveness of Recombinant Human Bone Morphogenetic Protein-2 for Spinal Fusion: A Meta-analysis of Individual-Participant Data

This report has been verified by one or more authors of the original publication.

Ann Intern Med. 2013 Jun 18;158(12):877-89. doi: 10.7326/0003-4819-158-12-201306180-00005

Physical Therapy & Rehab
The Effect of Protein and Carbohydrate Supplementation on Strength Training Outcome of Rehabilitation in ACL Patients
J Orthop Res. 2006 Nov;24(11):2114-23