The efficacy & safety of various doses of fulranumab vs placebo for chronic LBP

Clin Ther. 2016 Jun;38(6):1435-50

Chrondroitin sulfate improves pain and function compared to placebo in the management of knee OA

Ann Rheum Dis. 2017 May 22. pii: annrheumdis-2016-210860. doi: 10.1136/annrheumdis-2016-210860. [Epub ahead of print]

Hyaluronic acid injection similar in symptom & structure of knee OA vs diacerein & placebo

Ann Rheum Dis. 2004 Dec;63(12):1611-7

Dronabinol increases pain threshold compared to placebo for functional chest pain over 4 weeks

Dis Esophagus. 2017 Feb 1;30(2):1-8. doi: 10.1111/dote.12455

Single-dose intra-articular bupivacaine significantly reduces pain after knee arthroscopy

Knee Surg Sports Traumatol Arthrosc. 2014 Jul;22(7):1517-28

Glucosamine + chondroitin reduced joint space narrowing at 2 years vs. placebo in knee OA

Ann Rheum Dis. 2015 May;74(5):851-8.

OARSI 2016: Glucosamine and chondroitin not more effective than placebo for knee OA

Delta 9-THC has better analgesic efficacy versus placebo for neuropathic pain over 6 hours

J Pain. 2008 Jun;9(6):506-21. doi: 10.1016/j.jpain.2007.12.010

Capsaicin provide comparable or better pain and functional improvement than placebo

Clin Drug Investig. 2011 Dec 1;31(12):877-82. doi: 10.2165/11593860-000000000-00000

Nabiximols improves multiple sclerosis spasticity compared to placebo over 12 weeks

Eur J Neurol. 2011 Sep;18(9):1122-31. doi: 10.1111/j.1468-1331.2010.03328.x

THC/CBD oromucosal spray is not better than placebo for diabetic neuropathy over 12 weeks

Diabetes Care. 2010 ;33(1):128-130. http://dx.doi.org/10.2337/dc09-1029

WCO-IOF 2016: Lasofoxifene, raloxifene, and placebo for BMD in postmenopausal women

AAOS 2016: High-dose hyaluronate reduces pain versus placebo for plantar fasciitis

Delta-9 THC Improves Pain and Spasticity Compared to Placebo for Multiple Sclerosis Over 2 Weeks

CMAJ. 2012 Jul 10;184(10):1143-50. https://dx.doi.org/10.1503/cmaj.110837

AAOS: Hyaluronic acid and placebo produce similar pain and functional outcomes for knee OA

Comparable efficacy with etoricoxib 30mg and ibuprofen 2400mg in treating hip or knee OA

Osteoarthritis Cartilage. 2007 Dec;15(12):1348-56. Epub 2007 Jul 16

Rofecoxib and celecoxib demonstrate similar, significant 6-week efficacy vs placebo in OA treatment

Curr Med Res Opin. 2006 Jan;22(1):199-210

WCO-IOF: Dynamic electroneurostimulation vs placebo for osteoporotic spine fractures

Celecoxib and naproxen beneficial in Asian patients with knee OA compared to a placebo

Int J Rheum Dis. 2016 Mar;19(3):262-70

Vertebroplasty for osteoporotic fractures yield no benefit over placebo at 2-years

J Bone Miner Res. 2014 Jun;29(6):1346-55.