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TKA: Sciatic nerve block equivalent to periarticular infiltration

J Arthroplasty. 2012 Dec;27(10):1806-11. doi: 10.1016/j.arth.2012.05.018. Epub 2012 Jul 5

RCT Arthroplasty Nerve Osteoarthritis Lower Extremity Knee Bone Femur Arthritis Levobupivacaine Morphine SNB Femoral Nerve FNB Periarticular Infiltration Sciatic Nerve Block - Hide

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AAOS2017: Periarticular infiltration versus femoral nerve block for analgesia after TKA

RCT Arthroplasty Nerve Lower Extremity Knee Bone Femur Pain Analgesia Femoral Nerve Block PAI Periarticular Infiltration - Hide

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Femoral nerve block + periarticular infiltration analgesia provides pain relief post-TKA

J Anesth. 2014 Oct;28(5):696-701.

RCT Arthroplasty Nerve Osteoarthritis Lower Extremity Knee Bone Femur Arthritis Pain Ropivacaine Epinephrine Remifentanil Anaesthesia SNB Femoral Nerve Block General Anesthesia Guided Periarticular Infiltration Analgesia Sciatic Nerve Block TKA Ultrasound - Hide

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No analgesic advantage of liposomal bupivacaine over ropivacaine for infiltration analgesia in TKA

J Arthroplasty. 2018 Aug;33(8):2455-2459. doi: 10.1016/j.arth.2018.02.083

RCT Arthroplasty Lower Extremity Knee Pacira EXPAREL Ropivacaine Epinephrine Ketorolac Clonidine Liposomal Bupivacaine Periarticular Infiltration Analgesia Saline - Hide

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COA 2015: Adductor canal NB+Periarticular infiltration effective in managing post TKA pain

RCT Arthroplasty Nerve Lower Extremity Knee Muscle Adductor Pain Ropivacaine Morphine Ketorolac Canal Peripheral Nerve Block Intraoperative Periarticular Infiltration Preoperatively Saline TKA - Hide

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No clear benefit of liposomal bupivacaine over plain bupivacaine for periarticular injection in TKA

J Arthroplasty. 2018 Aug;33(8):2460-2464 doi: 10.1016/j.arth.2018.03.014

RCT Arthroplasty Axial Skeleton Spine Lower Extremity Knee Pain Liposomal Bupivacaine Periarticular Infiltration Analgesia Periarticular Injection Saline - Hide

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AAOS2018: Additional liposomal bupivacaine infiltration to ISBPB of no benefit in TSA

RCT Shoulder & Elbow Upper Extremity Shoulder Morphine Arthroplasty Infiltration Interscalene Brachial Plexus Liposomal Bupivacaine - Hide

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Lumbar plexus block vs periarticular infiltration with ropivacaine or liposomal bupivacaine in THA

J Bone Joint Surg Am. 2017 Nov 1;99(21):1836-1845

RCT Arthroplasty Nerve Spine Lumbar Lower Extremity Hip Ropivacaine Epinephrine Morphine Liposomal Bupivacaine Nerve Block PAI-R Periarticular Infiltration Plexus Block - Hide

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Local infiltration analgesia controls early pain post-hip arthroplasty

J Pain. 2014 Aug;15(8):781-799

Meta-analysis Arthroplasty Lower Extremity Hip Pain Anaesthesia Analgesic Anesthesia Arthroscopy Blockade Control HA Immediate Infusion LIA Local Infiltration Analgesia Periarticular Infiltration Analgesia Placebo Replacement Wound Infiltration - Hide

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TKA: Postoperative opiate use lowered by intraoperative periarticular LIA

Acta Orthop. 2014 Dec;85(6):614-9.

RCT Arthroplasty Osteoarthritis Lower Extremity Knee Arthritis Levobupivacaine Ketorolac Oxycodone Adrenaline LIA Periarticular Local Infiltration Analgesia Placebo Saline - Hide

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Periarticular multimodal drug injections effective and safe analgesic for TKA

Knee Surg Sports Traumatol Arthrosc. 2014 Aug;22(8):1949-57. doi: 10.1007/s00167-013-2566-0. Epub 2013 Jun 20.

Meta-analysis Arthroplasty Lower Extremity Knee Epinephrine Anaesthesia Analgesic Injections Corticosteroid Local Infiltration Periarticular Multimodal Placebo Replacement TKA - Hide

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Periarticular infiltration demonstrated better analgesia and opioid-sparing effect vs FNB in ACLR

Arthroscopy. 2018 Jan;34(1):182-188

RCT Sports Medicine Nerve Bone Femur Joint Ligament Muscle Semitendinosus Pain EndoButton Ropivacaine Fentanyl Analgesia Anterior Cruciate Femoral Nerve Block FNB PAI Periarticular Infiltration Reconstruction - Hide

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PAI - with and without ACB - more effective than ACB alone for analgesia in total knee arthroplasty

J Bone Joint Surg Am. 2018 Jul 5;100(13):1141-1146. doi: 10.2106/JBJS.17.01177

RCT Arthroplasty Lower Extremity Knee Muscle Adductor Bupivacaine Morphine ACB Analgesia Canal Block PAI - Hide

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Periarticular analgesic cocktail injection effective in reducing pain after TKA

J Arthroplasty. 2010 Sep;25(6):851-7

RCT Arthroplasty Osteoarthritis Lower Extremity Knee Pain Methylprednisolone Fentanyl Analgesic Injections Injection Of Bupivacaine Periarticular Injection - Hide

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Local infiltration analgesia demonstrates better pain relief than regional blockade in TKA

Pain Physician. 2016 May;19(4):205-14

Meta-analysis Arthroplasty Nerve Lower Extremity Knee Pain Morphine Anaesthesia Anesthesia Blockade Epidural Analgesia LIA Local Infiltration Analgesia Peripheral Nerve Block Regional Block Replacement Rest TKA - Hide

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Periarticular multimodal drug injection safe and efficacious alternative to FNB in TKA

J Arthroplasty. 2015 Jul;30(7):1281-6.

Meta-analysis Arthroplasty Nerve Lower Extremity Knee Bone Femur Pain Analgesia Femoral Nerve Block FNB Local Infiltration Periarticular Injection Periarticular Multimodal Replacement TKA - Hide

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Similar analgesic efficacy between local infiltration analgesia and nerve block in TKA

Br J Anaesth. 2016 May;116(5):597-609

Meta-analysis Arthroplasty Nerve Lower Extremity Knee Bone Femur Morphine Anaesthetic Analgesic Anesthetic Technique Canal Block Femoral Nerve Block Intraarticular Infiltration Intraarticular Injection LIA Local Infiltration Analgesia Periarticular Infiltration Periarticular Injection Peripheral Nerve Block Regional Anaesthesia Regional Anesthesia Replacement Rest TKA - Hide

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TKA: Sciatic nerve block equivalent to periarticular infiltration

AAOS2017: Periarticular infiltration versus femoral nerve block for analgesia after TKA

Femoral nerve block + periarticular infiltration analgesia provides pain relief post-TKA

No analgesic advantage of liposomal bupivacaine over ropivacaine for infiltration analgesia in TKA

COA 2015: Adductor canal NB+Periarticular infiltration effective in managing post TKA pain

No clear benefit of liposomal bupivacaine over plain bupivacaine for periarticular injection in TKA

AAOS2018: Additional liposomal bupivacaine infiltration to ISBPB of no benefit in TSA

Lumbar plexus block vs periarticular infiltration with ropivacaine or liposomal bupivacaine in THA

Local infiltration analgesia controls early pain post-hip arthroplasty

TKA: Postoperative opiate use lowered by intraoperative periarticular LIA

Periarticular multimodal drug injections effective and safe analgesic for TKA

Periarticular infiltration demonstrated better analgesia and opioid-sparing effect vs FNB in ACLR

AAOS2018: Psoas compartment block versus PAI for postoperative analgesia in total hip arthroplasty

COA 2016: Motor sparing knee block versus periarticular infiltration for pain after TKA

Influences of route of acetaminophen administration and periarticular liposomal bupivacaine in TKA

PAI - with and without ACB - more effective than ACB alone for analgesia in total knee arthroplasty

Periarticular analgesic cocktail injection effective in reducing pain after TKA

Local infiltration analgesia demonstrates better pain relief than regional blockade in TKA

Periarticular multimodal drug injection safe and efficacious alternative to FNB in TKA

Similar analgesic efficacy between local infiltration analgesia and nerve block in TKA

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