AAOS2017: Periarticular infiltration versus femoral nerve block for analgesia after TKA .
Pragmatic Randomized Controlled Trial of Periarticular Infiltration versus Femoral Nerve Blockade for Early Pain Relief Following Total Knee Replacement Surgery
262 patients scheduled for total knee arthroplasty were randomized to either periarticular infiltration (PAI) analgesia or a femoral nerve block. Patients were assessed for pain, analgesic consumption, and functional measures over the first 2 days postoperatively, as well as patient-reported function and quality of life at 6-week follow-up. Significant differences observed between groups included lower analgesic consumption in the first 24 hours after surgery and higher knee flexion on POD2 in the PAI group compared to the FNB group. Otherwise, all outcome measures demonstrated no significant differences between groups.
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