OrthoEvidence - Search

Arthroplasty
Efficacy of Tranexamic Acid in Reducing Blood Loss and Transfusion Requirements in Primary Total Knee Arthroplasty: A Prospective Comparative Study.
J Orthop Case Rep. 2026 01-Jun;():. 10.13107/jocr.2026.v16.i06.7382

Arthroplasty
Ascorbic Acid reduces the hidden blood loss after Total Hip Arthroplasty: Insights from a Randomized Controlled Trial

Peri-Operative

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Efficacy and Safety of Tranexamic Acid Combined with Absorbable Hemostat in Reducing Perioperative Blood Loss in Total Knee Arthroplasty: A Prospective, Blinded, Randomized Controlled Trial.
J Bone Joint Surg Am. 2025 01-Oct;():. 10.2106/JBJS.24.01236

Trauma
Efficacy of intraoperative use of tranexamic acid in reducing blood loss from telescoping nail application in osteogenesis imperfecta. A randomized controlled trial.
Orthop Traumatol Surg Res. 2025 01-May;():. 10.1016/j.otsr.2024.103927

Osteoarthritis
The role of tranexamic acid and cryotherapy on acute postoperative pain and blood loss: a randomized controlled study following total knee arthroplasty.
Eur J Orthop Surg Traumatol. 2025 01-Jan;():. 10.1007/s00590-025-04174-y

Arthroplasty
Bone wax reduces blood loss after total hip arthroplasty: a prospective, randomized controlled study.
Front Med (Lausanne). 2023 01-Sep;():. 10.3389/fmed.2023.1246733

Spine
Efficacy and Safety of Tranexamic Acid on Hidden Blood Loss in Osteoporotic Vertebral Compression Fractures Patients Treated with Percutaneous Kyphoplasty: A Prospective Randomized Controlled Trial.
Ther Clin Risk Manag. 2024 01-Dec;():. 10.2147/TCRM.S494728

Peri-Operative
Comparison of total blood loss between limited tourniquet use and conventional tourniquet use in total knee arthroplasty: a randomized controlled trial.
BMC Musculoskelet Disord. 2024 01-Nov;():. 10.1186/s12891-024-08058-w

Arthroplasty
The Effect of Intravenous Tranexamic Acid on Perioperative Blood Loss, Transfusion Requirements, Verticalization, and Ambulation in Total Knee Arthroplasty: A Randomized Double-Blind Study.
Medicina (Kaunas). 2024 01-Jul;():. 10.3390/medicina60071183

Peri-Operative
The efficacy of temperature intervention combined with tranexamic acid in reducing blood loss and accelerating recovery during spinal fusion.
Medicine (Baltimore). 2023 01-Nov;():. 10.1097/MD.0000000000036407

Arthroplasty
Comparison of the Unipolar Electrocautery and the Bipolar Sealer in Reducing Blood Loss in Total Knee Arthroplasty: A Prospective, Randomized, Noninferiority Study.
Arthroplast Today. 2024 01-Oct;():. 10.1016/j.artd.2024.101509

Arthroplasty
Oral as compared to intravenous tranexamic acid to limit peri-operative blood loss associated with primary total hip arthroplasty: A randomised noninferiority trial.
Eur J Anaesthesiol. 2024 01-Jan;():. 10.1097/EJA.0000000000001950

Arthroplasty
Comparative study of carbazochrome sodium sulfonate and tranexamic acid in reducing blood loss and inflammatory response following direct anterior total hip arthroplasty: a prospective randomized controlled trial.
Int Orthop. 2023 01-Oct;():. 10.1007/s00264-023-05853-3

Arthroplasty
Blood Loss in Primary Unilateral Total Knee Arthroplasty with Limited Tourniquet Application: A Randomized Controlled Trial.
JB JS Open Access. 2023 01-Dec;():. 10.2106/JBJS.OA.23.00020

Arthroplasty

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

The effects of tourniquet use on blood loss and perioperative complications in total knee arthroplasty.
BMC Musculoskelet Disord. 2023 01-Oct;():. 10.1186/s12891-023-06979-6

Arthroplasty
Comparing intra-articular and intravenous route of tranexamic acid administration and evaluating its efficacy in preventing blood loss during hip replacement surgery

General Orthopaedics
Medullary cavity application of tranexamic acid to reduce blood loss in tibial intramedullary nailing procedures-a randomized controlled trial.
Int Orthop. 2023 01-Aug;():. 10.1007/s00264-023-05824-8

Spine
The effect of sequential perioperative intravenous tranexamic acid in reducing postoperative blood loss and hidden blood loss after posterior lumbar interbody fusion: a randomized controlled trial.
Front Med (Lausanne). 2023 01-Aug;():. 10.3389/fmed.2023.1192971

Trauma
Tranexamic Acid Administered at Time of Hospital Admission Does Not Decrease Transfusion Rates or Blood Loss for Extracapsular Hip Fractures: A Double-Blinded Randomized Clinical Trial

Trauma
OTA 2023: TXA for Blood Loss and Transfusion Rates for Femur Fractures