OrthoEvidence - Search

General Orthopaedics
Antibiotic duration in native and periprosthetic joint infections : a systematic review and meta-analysis of randomized controlled trials.
Bone Jt Open. 2026 01-Mar;():. 10.1302/2633-1462.73.BJO-2025-0227.R2

Trauma

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Antibiotics in the treatment of low-velocity gunshot-induced fractures: a systematic literature review

This report has been verified by one or more authors of the original publication.

Clin Orthop Relat Res. 2013 Dec;471(12):3937-44. doi: 10.1007/s11999-013-2884-z

Arthroplasty
Success of Seven-Day Intra-Articular Antibiotic Irrigation for the Treatment of Chronic Periprosthetic Joint Infection: 12-Month Results from Two Prospective Randomized Comparative Studies.

Arthroplasty
Extended Oral Antibiotics Prevent PJI in High-Risk Cases: A Prospective, Randomized Controlled Trial

Arthroplasty
Success of Seven-Day Intra-Articular Antibiotic Irrigation for the Treatment of Chronic PJI

Pediatric Orthopaedics
Effect of Antibiotic Prophylaxis on Infection Rates in Pediatric Supracondylar Humerus Fractures Treated with Closed Reduction and Percutaneous Pinning: A Prospective Double-Blinded Randomized Controlled Trial.
J Am Acad Orthop Surg. 2024 01-May;():. 10.5435/JAAOS-D-23-00795

Peri-Operative
Multicentre randomised double-blind placebo controlled trial of combintion vancomycin and cefazolin surgical antibiotic prophylaxis: the Australian surgical antibiotic prophylaxis (ASAP) trial

Arthroplasty
Extended Surgical Antibiotic Prophylaxis Not Superior To A Single Dose In Total Hip And Knee Revision Arthroplasty: A Multicenter Open-Lavel Randomized Controlled Trial

Sports Medicine
Evaluation the results of anterior cruciate ligament reconstruction with or without using antibiotic solution during graft preparation.
Eur J Orthop Surg Traumatol. 2023 01-Oct;():. 10.1007/s00590-023-03522-0

Arthroplasty
Is Topical Vancomycin an Option? A Randomized Controlled Trial to Determine the Safety of the Topical Use of Vancomycin Powder in Preventing Postoperative Infections in Total Knee Arthroplasty, as Compared With Standard Postoperative Antibiotics.
J Arthroplasty. 2023 01-Aug;():. 10.1016/j.arth.2023.01.040

Arthroplasty
High-dose dual-antibiotic loaded cement for hip hemiarthroplasty in the UK (WHiTE 8): a randomised controlled trial

This report has been verified by one or more authors of the original publication.

Lancet. 2023 01-Jun;():. 10.1016/S0140-6736(23)00962-5

Tumour
The anti-infective outcomes of the distal femoral replacement coated with antibiotic cement in limb salvage surgery: A randomized clinical trial.
Medicine. 2022 01-Jan;():. 10.1097/MD.0000000000028648

Tumour
A Trial Comparing Prophylactic Intravenous Antibiotic Regimens Following Endoprosthetic Reconstruction for Lower Extremity Bone Tumors
JAMA Oncol. ;():. n/a

Peri-Operative

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Oral versus Intravenous Antibiotics for Bone and Joint Infection
N Engl J Med. 2019 ;():. 10.1056/NEJMoa1710926

General Orthopaedics
How Successful Is Antibiotic Treatment for Superficial Surgical Site Infections Following Open Fracture? A FLOW Trial Cohort Secondary Analysis

Trauma
Improved Healing of Severe Open Long Bone Fractures Treated with AntibioticFormulated Bone Graft During the First Surgical Intervention Post-Injury

Trauma
Does Topical Vancomycin Powder Use in Fracture Surgery Change Bacteriology and Antibiotic Susceptibilities? An Analysis of the VANCO Trial

General Orthopaedics

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Four versus six weeks of antibiotic therapy for osteoarticular infections after implant removal: a randomized trial
J Antimicrob Chemother. 2019;74(8)2394-2399. doi: 10.1093/jac/dkz202

General Orthopaedics
Is There a Difference in Infection Risk Between Single and Multiple Doses of Prophylactic Antibiotics? A Meta-analysis
Clin Orthop Relat Res. 2019 Jul;477(7):1577-1590.

Trauma

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Effect of Antibiotic Prophylaxis on Surgical Site Infections Following Removal of Orthopedic Implants Used for Treatment of Foot, Ankle, and Lower Leg Fractures: A Randomized Clinical Trial

This report has been verified by one or more authors of the original publication.

JAMA. 2017 Dec 26;318(24):2438-2445