COVID-19 Variants of Concern: Will There Be A Third Wave ?
OrthoEvidence Journal (OE Journal) - OE Original
OE Journal. 2021;9(4):3Multiple SARS-CoV-2 variants of concern—B.1.1.7, B.1.351, and P.1—have spread rapidly worldwide and demonstrate features that heighten global risk. Evidence suggests these variants are more transmissible, may increase disease severity, raise the likelihood of reinfection, and reduce the neutralizing activity of vaccine-elicited antibodies. Variants carrying the E484K mutation, notably B.1.351 and P.1, appear most concerning for potential vaccine escape. Although current data are limited and largely preprint, the cumulative evidence points to a realistic possibility of a third wave driven by VOCs, underscoring the need for immediate, strict, and sustained public health measures.
Unlock the Full original article
You have access to 4 more FREE articles this month.
Click below to unlock and view this original article
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
Are you affiliated with one of our partner associations?
Click here to gain complimentary access as part your association member benefits!