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OE JOURNAL

OE Journal

Vol. 8 | Iss. 21 | November 2020 - 20 Studies

ORIGINAL ANALYSIS

Monoclonal Antibodies: Does Regeneron Have A Cure?

The search for a COVID-19 cure has sparked enormous public excitement, and monoclonal antibody cocktails—especially REGN-COV2—have quickly risen to the spotlight following high-profile endorsements. Early trial results suggest these lab-engineered antibodies can lower viral load and reduce medical visits in outpatients, but the evidence is still based on relatively small studies with limited diversity and short follow-up. Important uncertainties remain, including who benefits most, how feasible mass manufacturing would be, and whether real-world delivery challenges could limit impact. Antibody therapies also appear to work best early in infection, requiring rapid testing and timely access—conditions not easily met during surges. While encouraging, the current data are far from definitive, and large, pragmatic RCTs are still needed before monoclonal antibodies can be considered a reliable solution.

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Full Issue Content

Arthroplasty 1
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Local Infiltration Analgesia Superior to Intrathecal Morphine for Pain Management in TJA Patients
Foot & Ankle 2
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No Benefit of Stretching Exercise to Monophasic Pulsed Current for Pain in Plantar Fasciitis Patient
General Orthopaedics 4
Osteoarthritis 1
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Acute Post-op Clinical Benefit with Transdermal Buprenorphine Patch vs Oral Celecoxib in TKA Patient
Pediatric Orthopaedics 1
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Ibuprofen Does Not Impair Long Bone Fracture Healing in Pediatric Fracture Patients
Physical Therapy & Rehab 4
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Increased Functionality and Strength in Non-Dominant Hand with Virtual Reality Video-Game Therapy
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Reduction in Kinesiophobia Scores in Patients Using Knee Bracing for Patellofemoral Pain
Shoulder & Elbow 2
Spine 3
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Intravenous Corticosteroid Before Spinal Surgery Improves Clinical Outcomes Compared to Placebo
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