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Volume:2 Issue:6 Number:24 ISSN#:2563-5476
Author Verified
RCT
ACE Report #4921
Ace Report Cover Spine

Low back pain: decrease in pain and disability with Modic antibiotic spine therapy


How to Cite

OrthoEvidence. Low back pain: decrease in pain and disability with Modic antibiotic spine therapy. ACE Report. 2013;2(6):24. Available from: https://myorthoevidene.com/AceReport/Report/4921

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Antibiotic treatment in patients with chronic low back pain and vertebral bone edema (Modic type 1 changes): a double-blind randomized clinical controlled trial of efficacy

Eur Spine J. 2013 Apr;22(4):697-707. doi: 10.1007/s00586-013-2675-y. Epub 2013 Feb 13

Contributing Authors: HB Albert JS Sorensen BS Christensen C Manniche

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OE EXCLUSIVE

Dr. Hanne Albert discusses antibiotic treatment in patients with chronic low back pain and vertebral bone edema (Modic type 1 changes).

Synopsis

162 patients (144 of whom completed the 1-year follow-up) suffering from chronic low back pain and Modic type 1 changes (bone edema in vertebrae) were randomized to either receive one of two dosing regimens of antibiotic or placebo tablets 3 times a day, for 100 days. Results indicated that there was a significant improvement in pain, disability and all other secondary outcomes reported in the ant...

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