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Analgesic Efficacy of Gabapentin in Patients Undergoing Carpal Tunnel Release Surgery

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Ace Report Cover
March 2025

Analgesic Efficacy of Gabapentin in Patients Undergoing Carpal Tunnel Release Surgery

Vol: 307| Issue: 3| Number:90| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Analgesic Efficacy of Gabapentin in Patients Undergoing Carpal Tunnel Release Surgery: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials.

Cureus. 2025 Jan 22;17(1):e77808.

Contributing Authors:
MN Alotaibi OY Alasmari OE Elshaer IS Allehaimeed HA Alharbi AA Alsubaiei AM Alharran A Alqallaf M Alshammari A Alhuwailah AF AlFaleh

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Synopsis

Three randomized controlled trials including 205 patients with carpal tunnel syndrome were included in this systematic review and meta-analysis comparing perioperative gabapentin versus placebo. Pooled outcomes of interest included postoperative pain at one, six, 12, and 24 hours, and the incidence of adverse events. Gabapentin significantly reduced postoperative pain at six, 12, and 24 hours, but...

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