WCO-IOF 2016: Greater BMD increase after 1 year of romosozumab vesus teripratide .
Superior gains in bone mineral density and estimated strength at the hip for romosozumab compared with teriparatide in women with postmenopausal osteoporosis transitioning from bisphosphonate therapy
436 postmenopausal women with osteoporosis who had been administered oral bisphosphonate therapy for 3 years prior were randomized in a phase 3 clinical trial to subcutaneous romosozumab or subcutaneous teriparatide. The purpose of this study was to compare the change in bone mineral density after 1 year of treatment between the two groups. Reported results demonstrated a significantly greater increase in total hip and lumbar spine BMD in the romosozumab group compared to the teriparatide group.
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