Low intensity pulsed ultrasonography for fractures: systematic review of randomised controlled trials

この研究はハイインパクトの可能性があります。 OEのAI駆動型ハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文が持つ可能性の高い影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することが可能になり、読者は将来の診療を形成する可能性が最も高い論文に集中することができます。

13 randomized controlled trials comparing low intensity pulsed ultrasonography to a control group, in patients with any fracture type, were included. The purpose of this systematic review and meta-analysis was to assess the efficacy of this treatment by systematically analyzing the available body of evidence. The pooled analysis across all trials (ie. all treatment inidications) displayed a significant reduction in radiographic healing time with low intensity pulsed ultrasonography compared to control. When treatment indications were assessed individually, LIPUS displayed accelerated functional improvements in operatively managed distraction osteogenesis and accelerated healing time in operatively managed non-union with bone-graft and non-operatively managed fresh fractures. Very low level evidence indicated the potenital for acceledrated healing in operatively treated fresh fractures. Overall, the results of this meta-analysis are conflicting and based on moderate to low-quality evidence. While the results show some promise for the use of low intensity pulsed ultrasound further high-quality trials are needed to identify the role it should play in different patient populations.