Riassunto dello studio

Thirty-one patients with cerebral palsy undergoing surgical treatment for hip dislocation were randomized to receive either tranexamic acid (TXA; n=21) or a placebo (control; n=10). The outcomes of interest were intraoperative bleeding, preoperative and 24-hour postoperative hemoglobin concentrations, length of hospital stay (LHS), and the necessity for blood transfusions. Outcomes were assessed up to 24 hours post-surgery. Overall, the results of the study revealed that TXA significantly reduced intraoperative bleeding as compared to the control group. The drop in hemoglobin concentration was lower in the TXA group, though this was not statistically significant, and no significant difference in LHS or the number of transfusions was noted. Ultimately, these findings suggest the effectiveness of TXA in reducing intraoperative bleeding without significant impacts on other measured outcomes.