TKR: Periarticular injection of 0.25% bupivacaine reduces morphine consumption .
Periarticular Injection with Bupivacaine for Postoperative Pain Control in Total Knee Replacement: A Prospective Randomized Double-Blind Controlled Trial
Adv Orthop. 2012;2012:107309. doi: 10.1155/2012/107309. Epub 2012 Oct 2260 osteoarthritis patients undergoing total knee arthroplasty (TKA) were randomized to receive a periarticular injection of bupivacaine or saline prior to closure of the wound. Over the first 6 hours after surgery, patients in the bupivacaine group consumed significantly less morphine than the saline group. However, this difference was not significant between 6 and 96 hours after the operation. The two groups also did not differ in the occurrence of wound complications, pain, morphine side effects, and length of stay at the hospital over 96 hours.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
