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Arthroplasty

TKA: Postoperative opiate use lowered by intraoperative periarticular LIA

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ARTHROPLASTY

TKA: Postoperative opiate use lowered by intraoperative periarticular LIA .

This report has been verified by one or more authors of the original publication.

Single periarticular local infiltration analgesia reduces opiate consumption until 48 hours after total knee arthroplasty. A randomized placebo-controlled trial involving 56 patients.

Acta Orthop. 2014 Dec;85(6):614-9.

Contributing Authors

M Niemeläinen J Kalliovalkama AJ Aho T Moilanen A Eskelinen

60 patients undergoing primary total knee arthroplasty were randomized to receive either a periarticular local infiltration analgesia (LIA) with levobupivacaine, ketorolac, and adrenaline versus a placebo injection of saline. Oxycodone consumption, pain, and range of motion were measured over 48 hours postoperatively, and functional outcomes were evaluated 1 year following surgery. The results of this study suggest that LIA reduced cumulative oxycodone consumption over the first 24 postoperative hours, with effect mainly occurring within the first 6 hours after surgery. Knee range of motion was also greater at 6 hours in those who received LIA, though no significant differences were detected at 24 and 48h. Functional outcomes were similar between groups at 1 year.

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