Tapentadol IR 50/75mg effective for pain control after Chevron osteotomy in Asian patients .
Acute postoperative pain relief with immediate-release tapentadol: randomized, double-blind, placebo-controlled study conducted in South Korea
Curr Med Res Opin. 2014 Dec;30(12):2561-70.353 patients, in South Korea, undergoing a distal Chevron osteotomy for unilateral hallux valgus were randomized to receive either 50 mg or 75 mg of tapentadol immediate-release, or placebo treatment. The purpose of this study was to understand the clinical effects of the drug in Asian patients. Pain intensity and relief from pain were measured using various numerical rating scales at 12, 24, 48 and 72 hours along with clinical laboratory tests evaluated postoperatively. The results indicated that both tapentadol immediate-release 50mg and 75mg group experienced lower pain intensity and greater pain relief as compared to the placebo group. Patients treated with tapentadol at either dose more frequently experienced mild-moderate treatment-emergent adverse events, such as nausea, dizziness, and vomiting.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
