The WHiTE 5 Trial: Cemented vs. Uncemented Hemiarthroplasty for Intracapsular Hip Fracture .
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Cemented or Uncemented Hemiarthroplasty for Intracapsular Hip Fracture
N Engl J Med. 2022 Feb 10;386(6): 521-530.1225 elderly patients with displaced intracapsular hip fractures were included in this multicentered, randomized controlled trial comparing cemented hemiarthroplasty and uncemented hemiarthroplasty. The primary outcome of interest was health-related quality of life at 4 months, measured with the EuroQol 5-Dimension 5-Level (EQ-5D-5L) instrument. Secondary outcomes of interest included EQ-5D scores at 1 and 12 months, the incidence of complications, mobility status, and residential status on hospital discharge. The results revealed significantly better health-related quality of life at 4 months in the cemented hemiarthroplasty group. Moreover, the odds of periprosthetic fracture was significantly higher in the uncemented hemiarthroplasty group.
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