The efficacy of kyphoplasty in the treatment of vertebral compression fractures .
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Efficacy and safety of balloon kyphoplasty compared with non-surgical care for vertebral compression fracture (FREE): A randomised controlled trial
Lancet. 2009 Mar 21;373:1016-24. Epub 2009 Feb 24300 patients with one to three vertebral fractures were randomized to receive balloon kyphoplasty or non-surgical treatment to assess the efficacy and safety of kyphoplasty. There were significant improvements in quality of life, pain, and function measures at one month follow-up in the kyphoplasty group when compared to the non-surgical group. However, these differences diminished over time and were no longer significant at a 1 year follow-up.
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