Subgroup analysis of treatments for patients suffering from sciatica .
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Timing of surgery for sciatica: Subgroup analysis alongside a randomized trial
Eur Spine J. 2009 Apr;18(4):538-45. Epub 2009 Jan 9Exclusive Author Interview
Surgical timing and its effect on clinical outcomes of sciatica with Dr. Peul
283 patients suffering from sciatica, identified by radiological confirmation of expected disc herniation, were either randomized to a prolonged conservative treatment (delayed surgical intervention if necessary) or to an early surgical intervention. The results indicated that conservative treatment produced similar results as the early surgical intervention at one year. This study also performed a secondary analysis of different subgroups within the patient population to identify determinants of recovery time in both procedures. The analysis identified sciatic pain upon sitting, as an indicator for early surgical intervention.
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