Subcutaneous Teriparatide for Pelvic Fracture Healing: A Phase 2 Randomized Controlled Trial .
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Teriparatide and pelvic fracture healing: a phase 2 randomized controlled trial.
Osteoporos Int. 2022 Jan;33(1): 239-250.Thirty-five patients over the age of 50 with an acute pelvic fracture were randomized to receive 3 months of subcutaneous teriparatide injections (n=18) or placebo injections (n=17). Outcomes of interest included pain scores on a Numeric Rating Scale (NRS), physical performance scores (Continuous Summary Physical Performance Score [CSPPS]; timed up and go), and bone healing. Results revealed no significant differences between the two groups in all outcomes, with the exception of CSPPS scores which were in favour of the teriparatide group at 2-3 months.
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