45 pediatric patients with adolescent idiopathic scoliosis were randomized to a Schroth exercise program administered either clinically or at home, or to a control group. The purpose of this study was to assess the effects of the clinically administered Schroth method on the Cobb angle, rib hump, vertebral rotation, waist asymmetry, and quality of life in these patients. The results displayed that the clinically administered program resulted in significant improvements over the home based group and control group, from baseline to week 24, in all assessed outcomes, with the exception of quality of life scores, which were similar across all groups. The home exercise group displayed comparable results to that of the control group that did not receive treatment for all outcomes.