Risk-Stratified Care Improves Pain Knowledge and Reduces Distress in Low Back Pain .
Risk-stratified Care Improves Pain-related Knowledge and Reduces Psychological Distress for Low Back Pain: A Secondary Analysis of a Randomized Trial.
Clin Orthop Relat Res . 2025 Apr 1;483(4):607-620.In this secondary analysis, our of two hundred and ninty patients with low back pain (LBP) two hundred and fifty nine were analyzed after randomization, to risk-stratified, psychologically-informed physical therapy (n=129) or usual care (n=130). The primary outcome was pain beliefs at 6 weeks assessed by the revised Neurophysiology of Pain Questionnaire (rNPQ, knowledge) and the Survey of Pain Attitudes—harm subscale (SOPA-h, attitudes). The secondary outcome was pain-related psychological distress quantified by OSPRO-Yellow Flags (count of “yellow flags” across 11 constructs). Outcomes were assessed at baseline and 6 weeks using adjusted models. Overall, the results revealed small but statistically significant improvements in rNPQ and reductions in OSPRO yellow-flag count with risk-stratified care versus usual care, while SOPA-h did not differ. In short, immediate post-treatment changes favored risk-stratified care for knowledge and distress, suggesting early cognitive-affective benefits that may mediate later clinical outcomes.
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