rhBMP -12/absorbable collagen sponge is a safe & feasible adjuvant for rotator cuff repair .
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Local rhBMP-12 on an Absorbable Collagen Sponge as an Adjuvant Therapy for Rotator Cuff Repair- A Phase 1, Randomized, Standard of Care Control, Multicenter Study: Part 1. Safety and Feasibility
Am J Sports Med. 2015 Jun 1. pii: 036354651558475620 patients with full-thickness rotator cuff tears were randomized to either a standard care treatment or 0.015mg/mL rhBMP-12/ACS along with standard care treatment during open rotator cuff repair to assess the safety and feasibility of recombinant human bone morphogenetic protein-12 (rhBMP-12) on an absorbable collagen sponge (ACS) as an adjuvant. Patients were followed for 52 weeks postoperatively. Findings indicated that rhBMP-12/ACS was a safe and feasible option for open rotator cuff repair when used at a concentration of 0.015 mg/mL.
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