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Previous Ace Report Acute effect of ayahuasca on neuropsychological performance between experienced and occasional users Next Ace Report Acute effect of ayahuasca on neuropsychological performance between experienced and occasional users
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Rapid and sustained decrease in suicidality following a single dose of ayahuasca
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Psychopharmacology (Berl)
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Rapid and sustained decreases in suicidality following a single dose of ayahuasca among individuals with recurrent major depressive disorder: results from an open-label trial

OrthoEvidence Journal (OE Journal) - ACE Report

OE Journal. 2022;10(12):6 Psychopharmacology (Berl). 2021 11-Apr;():. 10.1007/s00213-020-05692-9
Contributing Authors

RJ Zeifman N Singhal RG Dos Santos RF Sanches F de Lima Osório JEC Hallak CR Weissman

Study Summary

A secondary analysis of a case series of 17 patients with major depressive disorder examined the effects of a single dose of ayahuasca on suicidality. Suicidality was assessed using the suicidality subscale of the Montgomery-Asberg Depression Rating Scale (MADRS-SI). The study found a decrease in suicidality beginning 40 minutes after ingestion of ayahuasca, which continued decreasing to 21 days after ingestion of the single dose. The improvements were significant at all timepoints.

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How to cite this ACE Report

OrthoEvidence. Rapid and sustained decrease in suicidality following a single dose of ayahuasca. OE Journal. 2022;10(12):6. Available from: https://myorthoevidence.com/AceReport/Show/rapid-and-sustained-decrease-in-suicidality-following-a-single-dose-of-ayahuasca

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