SHOULDER & ELBOW
Platelet-rich plasma provides modest but durable functional benefit over corticosteroid for rotator cuff tendinopathy: A systematic review and meta-analysis of randomized controlled trials.
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OrthoEvidence Journal (OE Journal) - ACE Report
Epub Ahead of Print
Knee Surg Sports Traumatol Arthrosc. 2026 07-Sep;():. 10.1002/ksa.70416Study Summary
10 randomized controlled trials (RCTs) involving 591 patients with rotator cuff tendinopathy or partial-thickness tears were included in this systematic review and meta-analysis comparing platelet-rich plasma (PRP) versus corticosteroid (CS) injections. Pooled outcomes included pain measured using the visual analogue scale (VAS), shoulder function assessed using the American Shoulder and Elbow Surgeons (ASES) score and Constant–Murley score (CMS), and adverse events. At 3–6 weeks and 3 months, pain and functional outcomes were comparable between groups. However, PRP significantly improved pain and shoulder function at 6 months and was associated with fewer adverse events. These findings suggested that PRP provided modest but more sustained benefits than CS injections, although the clinical relevance of several improvements remained limited.
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