Oral Midodrine for Post-Spinal Anesthesia Hypotension During Hip Arthoplasty .
Oral midodrine for prophylaxis against post-spinal anesthesia hypotension during hip arthroplasty in elderly population: a randomized controlled trial.
BMC Anesthesiol . 2024 Feb 14;24(1):64.58 elderly patients undergoing hip arthroplasty under spinal anesthesia were randomized to receive either 5 mg oral midodrine (n=29) or a placebo (n=29). The primary outcome of interest was intraoperative ephedrine consumption. Secondary outcomes included the incidence of post-spinal hypotension, bradycardia, hypertension, mean arterial pressure (MAP), and heart rate (HR). Outcomes were assessed throughout the duration of the surgery. Overall, the results of the study revealed that the midodrine group had significantly lower intraoperative ephedrine consumption and a reduced incidence of hypotension compared to the control group. The findings suggest that oral midodrine is effective in decreasing vasopressor requirements and the incidence of hypotension in elderly patients undergoing hip arthroplasty.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
