No Significant Differences in Blood Loss or Clinical Outcomes with IA-TXA in ACL Reconstruction .
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original publication.
Intra-articular Administration of Tranexamic Acid Has No Effect in Reducing Intra-articular Hemarthrosis and Postoperative Pain After Primary ACL Reconstruction Using a Quadruple Hamstring Graft: A Randomized Controlled Trial.
Orthop J Sports Med. 2020 Jul; 8(7): 2325967120933135.Sixty patients scheduled for an anterior cruciate ligament (ACL) reconstruction for the treatment of an ACL tear were randomized to receive an intra-operative intra-articular injection of tranexamic acid (TXA) or no treatment. The primary outcome of interest was blood loss, calculated using hemoglobin levels. Secondary outcomes of interest included pain on a Visual Analog Scale (VAS), patellar circumference, range of motion and hemoglobin levels. No significant differences in all outcomes, at all time-points were observed between the TXA and control groups.
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