The Chitranjan S. Ranawat Award: Manipulation Under Anesthesia to Treat Postoperative Stiffness After Total Knee Arthroplasty: A Multicenter Randomized Clinical Trial.

この研究はインパクトが大きい可能性があると判断されました。 OEのAIによるハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文の影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することができ、読者は将来の診療を形成する可能性が最も高い論文に焦点を当てることができます。

研究概要

One hundred twenty-four patients with postoperative stiffness after primary TKA due to osteoarthritis were randomized to receive either MUA with PT alone (n=58) or MUA with PT plus one dose of pre-MUA intravenous dexamethasone (8 mg) and 14 days of oral celecoxib (200 mg) (n=66). The primary outcome of interest was knee ROM at 6 weeks after MUA. Secondary outcomes included knee ROM at 1 year and clinical outcome measures at both time points. Outcomes were assessed immediately after MUA, at 6 weeks, and at 1 year. Overall, the results revealed that while MUA significantly improved ROM immediately by 46°, there was no statistically significant difference between the treatment and control groups at 6 weeks or at 1 year. Clinical outcomes were also similar between groups. These findings suggest that the addition of dexamethasone and celecoxib does not enhance ROM or clinical outcomes after MUA for TKA stiffness.