Lysergic acid diethylamide tartrate (LSD-25) dosage levels, group differences and social interaction
OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2022;10(14):17 J Nerv Ment Dis. 1971 23-Feb;():. 10.1097/00005053-197108000-00008What this means for my practice?
These preliminary findings were presented given the lack of LSD research being completed during this time due to prohibitions. The exploratory findings will prompt further studies with more objective and standardized techniques to measure social behavioural changes. The results are limited by the small sample size, the lack of random dose administration and the lack of a suitable test for statistical significance of the findings.
Study Summary
Sixteen subjects who were either prison inmates, alcoholics or chronic schizophrenics underwent a study to examine the effects of LSD-25 on social behaviours, measured by the Bales Interaction Process Analysis technique. Subjects were organized into four groups of four, with an inmate group, two groups of alcoholics and a group of schizophrenics. Various doses of LSD were given. Total interaction increased at lower doses and decreased at higher doses. The effects observed depended on the group, with increased negative social-emotional behaviours in the inmates, increased positive behaviours in the alcoholic groups and an increase in both behaviours in the schizophrenics group.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
Are you affiliated with one of our partner associations?
Click here to gain complimentary access as part your association member benefits!
0 of 4 monthly FREE articles unlocked
