Seventy four patients (90 knees) were included in this study comparing uncemented tantalum trabecular metal monoblock tibial components and conventional cemented tibial components for the NexGen knee system (Zimmer) in terms of survivorship and clinical outcomes. Outcomes of interest included the Short Form 12 (SF-12) quality of life questionnaire, the Oxford Knee Score (OKS), the Knee Society Score (KSS), radiographic assessments, and the incidence of revision. Outcomes were assessed at 6 weeks, 1 year, 3 years, 5 years, and 11-15 years post-operation. OKS and KSS scores at 11-15 years were statistically significantly in favour of the uncemented group compared to the conventional group; however, no significant differences were observed at 1, 3, or 5 years post-operation. The 6-week data for OKS and KSS scores were missing. No significant differences in SF-12 scores were observed between the two groups at all timepoints. One case of revision was reported in the uncemented group. A statistically significant increase in radiolucency beneath the tibial trays was observed in the conventional group compared to the uncemented group.