Liposomal Bupivacaine Vs Conventional Bupivacaine After Total Knee Arthroplasty .
A prospective, randomized trial of liposomal bupivacaine compared to conventional bupivacaine on pain control and postoperative opioid use in adults receiving adductor canal blocks for total knee arthroplasty.
Arthroplasty . 2024 Feb 1;6(1):6.Eighty patients undergoing total knee arthroplasty were randomized to receive either liposomal bupivacaine (n=40) or conventional bupivacaine (n=40) in adductor canal blocks. The primary outcome of interest was pain scores within 72 hours postoperatively. Secondary outcomes included opioid consumption and length of hospital stay. Outcomes were assessed over a period of 72 hours post-surgery. Overall, the results of the study revealed that patients in the liposomal bupivacaine group had significantly lower opioid consumption during the 72-hour period, but there were no significant differences in pain scores or hospital stay between the groups. The findings suggest that liposomal bupivacaine may help reduce opioid use without impacting pain control or hospital length of stay.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
