Six randomized controlled trials containing a total of 1334 total knee arthroplasty patients were included in this meta-analysis comparing post-operative indwelling urinary catheterization (n=687) to no catheterization (n=647). Pooled outcomes of interest included urinary retention, urinary tract infection, length of hospital stay, duration of surgery, and time to first urination. Results of the meta-analysis demonstrated significantly greater risk of urinary tract infection (p=0.009) and longer time to first urination (p=0.004) in patients with indwelling urinary catheters than those without indwelling urinary catheters. No significant differences in pooled risk of urinary retention (p=0.52), length of stay (p=038) or duration of surgery (p=0.55) were observed between the two groups.