86 patients scheduled for anterior cruciate ligament reconstruction were randomized to receive an adductor canal block (ACB) or a femoral nerve block (FNB). Outcomes of interest included pain scores, morphine consumption, quadriceps muscle activation deficit, straight leg raise test, ambulation status, International Knee Documentation Committee (IKDC) score, extension range of motion deficit, flexion range of motion deficit, single-leg squat deficit, knee extension peak torque, anterior knee pain, knee extension loss, deep vein thrombosis and re-injury. Follow up was performed at 24 hours, 2 weeks, 4 weeks and 6 months. The findings from this study found significantly favourable quadriceps muscle activation deficit at 24 hours and 2 weeks in the ACB group. Additionally, a significantly higher proportion of patients met "full ambulation status" criteria at 4 weeks and a significantly lower proportion of patients had knee extension deficit at 6 months in the ACB group. Otherwise, there were no significant differences between groups.