A comparison of different exercise intensities for improving bone mineral density in postmenopausal women with osteoporosis: A systematic review and meta-analysis
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OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2022;10(23):12 Bone Rep. 2022 01-Oct;():. 10.1016/j.bonr.2022.101631What this means for my practice?
The results of this meta-analysis suggest that high-intensity resistance and impact training may provide significantly greater improvement in bone mineral density in the lumbar spine vs. moderate exercise for postmenopausal women with osteoporosis -- meta-analysis results also trended towards statistical significance in femoral neck bone mineral density, suggesting a potential benefit which should be explored in future trials. This study was limited by the small sample size, as well as the quality of the evidence which was lacking in several aspects: concerns with randomization were found in some studies, and selective reporting and "cherry-picking" of results have been identified and reported in the literature. Future high-quality randomized trials are required.
Study Summary
Six randomized controlled trials with a total of 391 women with post-menopausal osteoporosis were included in this meta-analysis comparing moderate- and high-intensity resistance and impact training. The primary outcome of interest was bone mineral density (BMD), measured in the lumbar spine and the femoral neck. Pooled results revealed significantly better BMD in the lumbar spine in the high-intensity group vs. the moderate-intensity group (p=0.04); pooled results for BMD in the femoral neck trended in favour of the high-intensity group (p=0.06). This study was limited by the limited sample size and the quality of the evidence.
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