Either etodolac 400mg bid or naproxen 500mg bid effective versus placebo in knee OA treatment .
Efficacy and safety of etodolac and naproxen in patients with osteoarthritis of the knee: a double-blind, placebo-controlled study
Clin Ther. 1995 Jul-Aug;17(4):656-66254 patients with symptomatic knee osteoarthritis were randomized to receive either etodolac 400mg, naproxen 500mg, or placebo for 4 weeks. Patients were assessed for clinical efficacy using Patients' and Physicians' Global Assessments, and safety was assessed using the incidence of adverse events. Both etodolac and naproxen demonstrated significantly better results for clinical efficacy compared to placebo, with no significant differences between etodolac and naproxen.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
