Effect of NSAID Blister Pack on Postoperative Opioid Use .
Scheduled, Simultaneous Dosing of Pregabalin, Celecoxib, and Acetaminophen Markedly Reduces or Eliminates Opioid Use After ACL Reconstruction Using Allograft or Hamstring Tendon Autograft: A Randomized Clinical Trial
Orthop J Sports Med . 2022 Dec 8;10(12):23259671221140837One hundred patients undergoing anterior cruciate ligament reconstruction (ACLR) with either an allograft or hamstring tendon autograft for ACL ruptures were randomized to either a blister pack of non-steroidal anti-inflammatory drugs (NSAIDs; n=50) or ibuprofen and opioids (n=50). Outcomes of interest were nausea, itching, and pain measured using the Verbal Numeric Rating Scale (VNRS) and oxycodone consumption after 6 days. No significant pairwise differences were apparent throughout the 6-day period for oxycodone use and pain scores. Nausea and itching were significantly lower in the blister pack group.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
