Degenerative Spondylolisthesis: Surgical treatment results in improved pain and function .
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Surgical versus Nonsurgical Treatment for Lumbar Degenerative Spondylolisthesis
N Engl J Med. 2007 May 31;356(22):2257-70607 patients with degenerative spondylolisthesis were enrolled in The Spine Patient Outcomes Research Trial (SPORT) which included both a randomized cohort as well as an observational cohort. In the randomized cohort, patients were randomized to receive either standard posterior decompressive laminectomy (surgical procedure) or non-surgical treatment for this condition. Those in the observational cohort chose their treatment with their physician. The as-treated comparisons completed for the combined cohorts indicated that surgical treatment for those with spinal stenosis and degenerative spondylolisthesis resulted in improved pain and function outcomes.
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