Comparison between 0.125% and 0.25% bupivacaine ISBPB in rotator cuff repair .
Diaphragm function after interscalene brachial plexus block: a double-blind, randomized comparison of 0.25% and 0.125% bupivacaine
J Shoulder Elbow Surg. 2013 Mar;22(3):381-6. doi: 10.1016/j.jse.2012.06.011. Epub 2012 Sep 130 patients undergoing rotator cuff repair were randomized to receive ultrasound-guided interscalene brachial plexus block with either 20 mL of 0.125% bupivacaine or 0.25% bupivacaine, to compare the diaphragm function, oxygen saturation, and pain management outcomes between groups. Following evaluations over a 48 hour period, clinically similar pain management (VAS pain scores and opioid requirements) were experienced between the two groups, although diaphragm dysfunction and oxygen saturation decrease were significantly lessened among patients treated with the dilute bupivacaine preparation (0.125%).
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