Combination of peri-articular injection and auto-transfusion safe in TKA .
The safety of peri-articular local anaesthetic injection for patients undergoing total knee replacement with autologous blood transfusion: A randomised trial
J Bone Joint Surg Br. 2012 Dec;94(12):1632-6. doi: 10.1302/0301-620X.94B12.2935746 patients undergoing total knee replacement with an autotransfusion drain were randomized to receive either intra-operative peri-articular infiltration of local anaesthetic or a femoral nerve block to determine if the drain concentrations of levobupivacaine posed health and safety concerns during re-transfusion. Levobupivacaine levels were measured from blood serum samples taken pre-transfusion, from the re-transfusion drain, and post-transfusion. Concentrations of anaesthetic were found to be statistically higher in the drain samples of the peri-articular injection group, but were concluded as being non-toxic.
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