Cognitive Functional Therapy Outperforms Sham for Chronic Low Back Pain .
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Efficacy of cognitive functional therapy for pain intensity and disability in patients with non-specific chronic low back pain: a randomised sham-controlled trial.
Br J Sports Med . 2025 Jun 18;59(13):912-920.One hundred fifty-two patients with non-specific chronic low back pain (CLBP) were randomized to receive individualized cognitive functional therapy (CFT)(n=76) or a sham intervention (neutral talking plus detuned low-level laser; n=76). The primary outcomes were pain intensity (0–10) and Oswestry Disability Index (0–100) at 6 weeks. Secondary outcomes included pain and disability at 3 and 6 months, functioning, pain self-efficacy, global perceived effect, and analgesic use. Outcomes were assessed pre-treatment, post-treatment (6 weeks), and at 3 and 6 months. Overall, the results revealed clinically meaningful, statistically significant advantages for CFT over sham at 6 weeks that persisted through 6 months. In short, CFT produced durable improvements in pain, disability, functioning, and self-efficacy beyond contextual effects.
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