Clinical Efficacy Of Botulinum Toxin In Lateral Elbow Tendinopathy .
Clinical efficacy of botulinum toxin in lateral elbow tendinopathy: A systematic review and meta-analysis of randomized controlled trials.
Orthop Traumatol Surg Res . 2025 May;111(3):103733.Eight studies including 438 patients with chronic lateral elbow tendinopathy were included in this systematic review and meta-analysis comparing botulinum toxin injection vs. placebo or corticosteroid injections. Pooled outcomes of interest included pain reduction, grip strength, and adverse events. Botulinum toxin significantly reduced pain, but the reduction did not reach the minimal clinically important difference. There was no significant improvement in grip strength or increased risk of adverse events. Overall, botulinum toxin may modestly reduce pain in the short term, but the clinical relevance remains uncertain.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics