Clinical, but no ultrasonographic, improvement of lateral epicondylitis with 3 treatments .
OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2013;1(1):30 Clin Rheumatol. 2012 May;31(5):807-12. doi: 10.1007/s10067-012-1939-y. Epub 2012 Jan 2759 patients diagnosed with the condition lateral epicondylitis (LE), were randomised into three groups to undergo either physical therapy, a single corticosteroid injection, or extracorporeal shock wave treatment (ESWT), to determine which technique was the most effective in treating LE. Following assessments measured over 6 months, results displayed that all three methods used for LE treatment had positive outcomes regarding reduction in pain and an increase in grip strength in early stages. However, there were no differences in thickness and cortical abnormalities of the common extensor tendon and bony cortex of the lateral epicondyle, measured using the ultrasonography, prior to and 6 months after treatment.
Was the allocation sequence adequately generated?
Was allocation adequately concealed?
Blinding Treatment Providers: Was knowledge of the allocated interventions adequately prevented?
Blinding Outcome Assessors: Was knowledge of the allocated interventions adequately prevented?
Blinding Patients: Was knowledge of the allocated interventions adequately prevented?
Was loss to follow-up (missing outcome data) infrequent?
Are reports of the study free of suggestion of selective outcome reporting?
Were outcomes objective, patient-important and assessed in a manner to limit bias (ie. duplicate assessors, Independent assessors)?
Was the sample size sufficiently large to assure a balance of prognosis and sufficiently large number of outcome events?
Was investigator expertise/experience with both treatment and control techniques likely the same (ie.were criteria for surgeon participation/expertise provided)?
Ja = 1
Ungewiss = 0.5
Nicht relevant = 0
Nein = 0
Die Bewertung der Berichtskriterien bewertet die Transparenz, mit der die Autoren die methodischen und studienspezifischen Merkmale der Studie in der Veröffentlichung angeben. Die Bewertung ist in fünf Kategorien unterteilt, die im Folgenden vorgestellt werden.
2/4
Randomization
3/4
Outcome Measurements
4/4
Inclusion / Exclusion
4/4
Therapy Description
3/4
Statistics
Detsky AS, Naylor CD, O'Rourke K, McGeer AJ, L'Abbé KA. J Clin Epidemiol. 1992;45:255-65
Der Fragilitätsindex ist ein Instrument, das bei der Interpretation signifikanter Ergebnisse hilft und ein Maß für die Stärke eines Ergebnisses liefert. Der Fragilitätsindex gibt die Anzahl der aufeinanderfolgenden Ereignisse an, die zu einem dichotomen Ergebnis hinzugefügt werden müssen, damit das Ergebnis nicht mehr signifikant ist. Eine kleine Zahl steht für ein schwächeres Ergebnis und eine große Zahl für ein stärkeres Ergebnis.
Warum wurde diese Studie jetzt benötigt?
The most common condition associated with elbow pain is lateral epicondylitis (LE). LE results from the overuse of an injured extensor tendon of the dominant upper extremity. The condition is commonly treated through deep tendon friction massage, mobilization, physiotherapy exercises, stretching and strengthening exercises, splints, and local corticosteroid injections. Recently, shockwave therapy and Cyriax therapy have also been suggested to alleviate pain caused by LE. However, in the few comparisons that have been made between treatment types, the results have been conflicting. Hence, this study aimed to determine which of the treatment methods is more efficient in treating LE, through the clinical and ultrasonographic comparison of therapeutic effects.
Was war die wichtigste Forschungsfrage?
Were there any significant differences in outcomes between physical therapy, corticosteroid injection, and ESWT in patients with LE when compared clinically versus ultrasonographically, when measured over a 6 month period?
- Clinical findings indicated that there was a significant decrease in VAS scores for all three groups at months 1, 3, and 6 following treatment (p<0.001). VAS scores were similar for all three groups.
- Clinical results showed there was a significant increase in grip strength values on months 1 and 3 of treatment for Group I (Physiotherapy Group), month 1 for Group II (Injection Group), and months 1, 3, and 6 for Group III (ESWT Group) (Month 1, p<0.003; Months 3 and 6, p<0.001).
- However, ultrasonographic findings did not correlate with the results regarding improvement in pain scores and grip strength.
- There was no significant difference in pinch strength values between the three groups (p>0.05).
- There was no significant difference in the cortical irregularities of the extensor tendon prior to treatment and at 6 months of treatment for all three groups (p>0.05).
Was sollte ich mir besonders merken?
The clinical findings demonstrated similar reductions in pain, increases in grip strength and finger pinch strength in early stages of LE treatment with physical therapy, corticosteroid injection, and ESWT. However, these changes observed clinically were not supported ultrasonographically. Rather, no differences in thickness and cortical abnormalities of the common extensor tendon and bony cortex of the lateral epicondyle were seen when measured prior and 6 months after treatment.
Wie wird sich dies auf die Behandlung meiner Patienten auswirken?
Since clinical effects of the LE treatment were not supported ultrasonographically, confusion remains in what the long term effects of physical therapy, corticosteroid injection, and ESWT are. In future studies patients should be blinded in order to lower the potential risk of bias, the population size should be increased, and longer follow-up periods should be used.
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